N-Methylbenzylamine → HCID 18752898, compound

HRID 1838073Notes

Reaction equation

HRID 1838073 reaction equation
[NH2:1][C:2]1[C:7](/[CH:8]=[CH:9]/[C:10]([OH:12])=O)=[CH:6][C:5]([Cl:13])=[CH:4][N:3]=1.[CH3:14][NH:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.C(OC(C)C)(C)C>>[NH2:1][C:2]1[C:7](/[CH:8]=[CH:9]/[C:10]([N:15]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH3:14])=[O:12])=[CH:6][C:5]([Cl:13])=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 7669N-MethylbenzylamineHCID 7914Diisopropyl EtherHCID 18752895HCID 18752895, compound

Product 1

HCID 18752898HCID 18752898, compound

Procedure

The title compound was prepared from (E)-3-(2-amino-5-chloro-3-pyridinyl)-2-propenoic acid and N-methyl benzylamine as a yellow solid following crystallisation from diisopropyl ether:

Sources & evidence

ORD record
ord-d63dd649301847afb932278ad3bac44b
Source dataset
uspto-grants-2004_01
Patent number
US06673789B2

Reaction notes

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