Tetrahydrofuran → 4-(2-Fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridazine-3-carboxylic acid
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:24][Si:25]([N-:26][Si:27]([CH3:28])([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:1][c:2]1[c:3]([C:11](=[O:12])[OH:13])[n:4][n:5]([CH3:10])[c:6](=[O:9])[c:7]1[CH3:8].[F:14][c:15]1[c:16]([NH2:17])[cH:18][cH:19][c:20]([I:22])[cH:21]1.[Li+:23]>>[c:2]1([NH:17][c:16]2[c:15]([F:14])[cH:21][c:20]([I:22])[cH:19][cH:18]2)[c:3]([C:11](=[O:12])[OH:13])[n:4][n:5]([CH3:10])[c:6](=[O:9])[c:7]1[CH3:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-11b24367355741bc91811f84de676d9d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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