HCID 10945066, compound → HCID 10857172, compound

HRID 1838670Notes

Reaction equation

HRID 1838670 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]1[CH:16]=[CH:15][C:14]([N+:17]([O-])=O)=[CH:13][C:5]=1[C:6](=[O:12])[O:7]2>CN1CCCC1=O>[NH2:17][C:14]1[CH:15]=[CH:16][C:4]2[C:3]3[C:8](=[CH:9][CH:10]=[CH:11][C:2]=3[OH:1])[O:7][C:6](=[O:12])[C:5]=2[CH:13]=1

Participants

3

Reactant 1

HCID 10945066HCID 10945066, compound

Product 1

HCID 10857172HCID 10857172, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent2×

Procedure

treating 1-hydroxy-8-nitro-6H-benzo[c]chromen-6-one with a second transition metal catalyst under a hydrogen atmosphere at a pressure of about 20 to about 60 psi, preferably about 40 psi, in a third solvent, preferably N-methylpyrrolidin-2-one (NMP) at a concentration of about 0.5M to about 1.0M, preferably 0.7M, to provide 8-amino-1-hydroxy-6H-benzo[c]chromen-6-one in NMP;

Sources & evidence

ORD record
ord-d7a24758a73a420ea47c769db0fbe5b0
Source dataset
uspto-grants-2004_01
Patent number
US06673930B2

Reaction notes

Loading…