Tetrahydrofuran → (2-(4-Methylthiazol-2-ylamino)pyridin-4-yl)(phenyl)methanol

HRID 183885Notes

Reaction equation

HRID 183885 reaction equation
[Br:1][Mg:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[CH3:9][c:10]1[n:11][c:12]([NH:15][c:16]2[cH:17][c:18]([CH:19]=[O:20])[cH:21][cH:22][n:23]2)[s:13][cH:14]1>>[c:3]1([CH:19]([c:18]2[cH:17][c:16]([NH:15][c:12]3[n:11][c:10]([CH3:9])[cH:14][s:13]3)[n:23][cH:22][cH:21]2)[OH:20])[cH:4][cH:5][cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 86634740HCID 86634740, compoundHCID 178418255HCID 178418255, compound

Product 1

HCID 24826745(2-(4-Methylthiazol-2-ylamino)pyridin-4-yl)(phenyl)methanol

Sources & evidence

ORD record
ord-0b5bb8d9e9cb46509711dfbd8229c547
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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