Dimethylformamide → 13-chloro-5-[5-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-3-yl]-2,4,10-triazatetracyclo[10.4.0.02,6.07,10]hexadeca-1(16),3,5,12,14-pentaen-11-one

HRID 184059Notes

Reaction equation

HRID 184059 reaction equation
[CH2:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:25])[N:9]1[CH:10]([c:11]3[n:12]-2[cH:13][n:14][c:15]3-[c:16]2[n:17][o:18][c:19]([CH2:21][Cl:22])[n:20]2)[CH2:23][CH2:24]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:25])[N:9]1[CH:10]([c:11]3[n:12]-2[cH:13][n:14][c:15]3-[c:16]2[n:17][o:18][c:19]([CH2:21][N:29]3[CH2:28][CH2:27][CH2:26][CH2:31][CH2:30]3)[n:20]2)[CH2:23][CH2:24]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 8082PiperidineHCID 17851511913-chloro-5-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-2,4,10-triazatetracyclo[10.4.0.02,6.07,10]hexadeca-1(16),3,5,12,14-pentaen-11-one

Product 1

HCID 17851512113-chloro-5-[5-(piperidin-1-ylmethyl)-1,2,4-oxadiazol-3-yl]-2,4,10-triazatetracyclo[10.4.0.02,6.07,10]hexadeca-1(16),3,5,12,14-pentaen-11-one

Sources & evidence

ORD record
ord-ae06f87de55e4a4aa1d500517f76074e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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