Dichloromethane → HCID 11975073, compound

HRID 184286Notes

Reaction equation

HRID 184286 reaction equation
[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:40][S:41]([Cl:42])(=[O:43])=[O:44].[Cl:45][CH2:46][Cl:47].[NH2:8][c:9]1[n:10][c:11]([NH:26][CH:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:24][CH3:25])[cH:19][c:20]([F:23])[cH:21][cH:22]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:8][c:9]1[n:10][c:11]([NH:26][CH:27]2[CH2:28][CH2:29][N:30]([S:41]([CH3:40])(=[O:43])=[O:44])[CH2:31][CH2:32]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:24][CH3:25])[cH:19][c:20]([F:23])[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 210706264-Amino-2-(piperidin-4-ylamino)pyrimidin-5-yl-(4-fluoro-2-methoxy-phenyl)-methanone

Product 1

HCID 11975073HCID 11975073, compound

Sources & evidence

ORD record
ord-7b8b4b48149e4347a767fa7374d03e5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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