Nitromethane → 18984-16-2

HRID 1843926Notes

Reaction equation

HRID 1843926 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=O.[N+:11]([CH3:14])([O-:13])=[O:12].[OH-].[Na+]>C(O)C>[Cl:10][C:9]1[CH:8]=[CH:7][C:4]([CH:5]=[CH:14][N+:11]([O-:13])=[O:12])=[CH:3][C:2]=1[Cl:1]

Participants

5

Reactant 3

HCID 6375NitromethaneHCID 14798Sodium HydroxideHCID 227103,4-Dichlorobenzaldehyde

Product 1

HCID 23629018984-16-2Yield 75%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using an analogous reaction procedure and workup as described in Example 1, 3,4-dichloro-benzaldehyde (5.6 g, 41.481=01) in ethanol (56 mL) was reacted with nitro methane (2.3 mL, 41.481 mmol), 10N NaOH solution (1.65 g, 41.481 mmol) at 0° C. for 1 hour to afford 5.1 g of the product (75% yield).

Workup

  1. customan analogous reaction procedure

Sources & evidence

ORD record
ord-43a052d35d11408fbad1b69a26940f9a
Source dataset
uspto-grants-2015_02
Patent number
US08946260B2

Reaction notes

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