反应详情

3-(2-Ethoxy-2-oxoethyl)pyridine-1-oxide (I-67a: 4.8 g, 26.66 mmol) in iodoethane (7.67 mL, 95.99 mmol) was stirred at room temperature for 144 hours under nitrogen atmosphere. The reaction was monitored by TLC (10% methanol in chloroform). The reaction mass was concentrated under reduced pressure to afford 5.3 g of the crude product.

1. concentrationThe reaction mass was concentrated under reduced pressure