反应详情

To 4-methoxybenzamide (2.6 mmol) in dichloromethane (10 mL) was added oxalyl chloride 98% (6.61 mmol) dropwise. The mixture was heated to reflux for 20 h. Reaction completion monitored by TLC. The solvent was removed in vacuo (40° C., 760 mmHg) to obtain title compound D11, which was immediately used without purification.

1. temperatureThe mixture was heated
2. temperatureto reflux for 20 h
3. customReaction completion
4. customThe solvent was removed in vacuo (40° C., 760 mmHg)