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HRID1846111

反应详情

EQUATION

反应方程式

HRID 1846111 的结构方程式

REACTANTS

反应物

4
结构：CC(C)(C)C(=O)Cl
HCID62493

2,2-Dimethylpropanoyl chloride

C5H9ClO

结构：C[Si](C)(C)N=C(O[Si](C)(C)C)C(F)(F)F
HCID94358

N,O-Bis(trimethylsilyl)trifluoroacetamide

C8H18F3NOSi2

结构：CSc1[nH]c2cc(Br)cc(Br)c2c1SC
HCID14185853

4,6-Dibromo-2,3-bis(methylsulfanyl)-1H-indole

C10H9Br2NS2

结构：NCc1ccc(F)c(C(=O)O)c1F
HCID58483480

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)C(=O)NCc1ccc(F)c(C(=O)O)c1F
HCID58483339

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Prepared analogously to 44b with 3-aminomethyl-2,6-difluorobenzoic acid, Piv-Cl, BSTFA and TEA in THF. Yield: 1.2 g (77%); MS: [m+H]+=272; HPLC: Rt=1.38 min (Method MC-6)