HRID1846112

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14185853

4,6-Dibromo-2,3-bis(methylsulfanyl)-1H-indole

C10H9Br2NS2

结构：Cc1c(CNC(=O)C(F)(F)F)c(F)c(F)c(Cl)c1C(=O)O.Cc1c(F)c(F)c(CNC(=O)C(F)(F)F)c(Cl)c1C(=O)O

HCID131732429

未命名化合物

PRODUCTS

生成物

结构：Cc1c(CN)ccc(Cl)c1C(=O)O.Cc1ccc(CN)c(Cl)c1C(=O)O

HCID86658675

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

Prepared analogously to 44a with 2-chloro-6-methyl-difluoro-3-(trifluormethylcarbonylamino)methyl-benzoic acid/2-methyl-6-chloro-difluoro-3-(trifluormethylcarbonylamino)methyl-benzoic acid (5.62 g 19 mmol) in 6 M aq. HCl solution. Yield: 4.37 g; (97%; mixture of regioisomers); MS: [M−H]−=198; HPLC: Rt=0.189 min (Method MC-6)

WORKUP

后处理

addition(97%; mixture of regioisomers)