Water → HCID 91308289, compound

HRID 1846433Notes

Reaction equation

HRID 1846433 reaction equation
[CH3:1][C:2]1[C:7]2[NH:8][C:9](=[O:11])[O:10][C:6]=2[CH:5]=[C:4]([C:12]([N:14]=[N+:15]=[N-:16])=[O:13])[CH:3]=1.[C:17](=O)([O-])[O-].[K+].[K+].CI.O>CN(C=O)C>[CH3:17][N:8]1[C:7]2[C:2]([CH3:1])=[CH:3][C:4]([C:12]([N:14]=[N+:15]=[N-:16])=[O:13])=[CH:5][C:6]=2[O:10][C:9]1=[O:11]

Participants

6

Reactant 4

HCID 962WaterHCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 117860285HCID 117860285, compound

Product 1

HCID 91308289HCID 91308289, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

550 mg (2.50 mmol) 4-methyl-2-oxo-2,3-dihydro-benzoxazole-6-carboxylic acid azide and 400 mg (2.90 mmol) potassium carbonate were stirred in DMF for 20 min at RT. Then 0.200 mL (3.21 mmol) of methyl iodide were added and the mixture was stirred for 1.5 h at RT. Water was added to the reaction mixture, the precipitate formed was suction filtered and dried.

Workup

  1. customthe precipitate formed
  2. filtrationfiltered
  3. customdried

Sources & evidence

ORD record
ord-abe22b8e54c645ca941705012d3b1c41
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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