Dimethylformamide → HCID 66978224, compound

HRID 1846463Notes

Reaction equation

HRID 1846463 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].CN(C=O)C.[CH3:10][C:11]1[C:16]2[NH:17][C:18](=[O:20])[O:19][C:15]=2[CH:14]=[CH:13][CH:12]=1.[CH3:21][C:22](OC(C)=O)=[O:23]>O>[C:22]([C:13]1[CH:12]=[C:11]([CH3:10])[C:16]2[NH:17][C:18](=[O:20])[O:19][C:15]=2[CH:14]=1)(=[O:23])[CH3:21]

Participants

6

Reactant 4

HCID 6228DimethylformamideHCID 7918Acetic AnhydrideHCID 6451240Aluminum(III) ChlorideHCID 127093364-Methyl-3H-benzooxazol-2-one

Product 1

HCID 66978224HCID 66978224, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

20.0 g (149.99 mmol) aluminium(III) chloride were combined with 5.0 mL DMF, with cooling. After 15 min stirring, first of all 5.0 g (33.52 mmol) 4-methylbenzo[d]oxazol-2(3H)-one and then 5.0 mL (52.90 mmol) acetanhydride were added and the mixture was stirred for 1 h at 80° C. The cooled reaction mixture was mixed with water. The precipitate formed was suction filtered, washed and dried.

Workup

  1. temperaturewith cooling
  2. customThe cooled reaction mixture
  3. customThe precipitate formed
  4. filtrationfiltered
  5. washwashed
  6. customdried

Sources & evidence

ORD record
ord-94ee784c44584a9488698bc5c5d3780a
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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