N-(2-chloro-4-hydroxy-6-nitrophenyl)acetamid → 4-Amino-3-chloro-5-nitrophenol

HRID 1846489Notes

Reaction equation

HRID 1846489 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[C:4]([N+:9]([O-:11])=[O:10])[C:3]=1[NH:12]C(=O)C>Cl>[NH2:12][C:3]1[C:4]([N+:9]([O-:11])=[O:10])=[CH:5][C:6]([OH:8])=[CH:7][C:2]=1[Cl:1]

Participants

3

Reactant 1

HCID 66978135N-(2-chloro-4-hydroxy-6-nitrophenyl)acetamid

Product 1

HCID 669783384-Amino-3-chloro-5-nitrophenol

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

1.00 g (4.24 mmol) N-(2-chloro-4-hydroxy-6-nitrophenyl)acetamid were refluxed in 10 mL semiconcentrated hydrochloric acid for 2 h. The reaction mixture was evaporated down i.vac. and dried.

Workup

  1. customThe reaction mixture was evaporated down i.vac
  2. customand dried

Sources & evidence

ORD record
ord-992c43b86e70488788b654e6c27fc72b
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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