反应详情

62 mg (0.23 mmol) 7-methoxy-3-piperidin-4-yl-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one, 50 mg (0.21 mmol) 6-chloro-N-(2,6-dimethylpyridin-4-yl)pyrimidin-4-amine and 0.10 mL (0.57 mmol) DIPEA in 1.0 mL DMF were stirred for 1 h at 90° C. The reaction mixture was mixed with water and the precipitate formed was suction filtered and dried.

1. customthe precipitate formed
2. filtrationfiltered
3. customdried