Hydrochloric Acid → 2-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-4,4,6,6-tetramethyl-N-prop-2-ynyl-4,6-dihydrothieno[2,3-c]furan-3-carboxamide

HRID 184658Notes

Reaction equation

HRID 184658 reaction equation
[CH2:31]([C:32]#[CH:33])[NH2:34].[ClH:30].[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([C:19](=[O:20])[OH:21])[c:9]3[c:10]([s:18]2)[C:11]([CH3:16])([CH3:17])[O:12][C:13]3([CH3:14])[CH3:15])[c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][cH:24][cH:25]1>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([C:19](=[O:21])[NH:34][CH2:31][C:32]#[CH:33])[c:9]3[c:10]([s:18]2)[C:11]([CH3:16])([CH3:17])[O:12][C:13]3([CH3:14])[CH3:15])[c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][cH:24][cH:25]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 239041PropargylamineHCID 67300640HCID 67300640, compound

Product 1

HCID 247726822-{[2-fluoro-6-(trifluoromethyl)benzoyl]amino}-4,4,6,6-tetramethyl-N-prop-2-ynyl-4,6-dihydrothieno[2,3-c]furan-3-carboxamide

Sources & evidence

ORD record
ord-bf90a87b63ee4e41af104a1694c56e85
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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