Dimethylformamide → 5-(6-(2-hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-(3-(trifluoromethyl)phenyl)-1H-indole-1-carboxamide
Reaction equation
[Br:33][CH2:34][CH2:35][OH:36].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[n:1]1[cH:2][n:3][c:4]([O:10][c:11]2[cH:12][c:13]3[cH:14][cH:15][n:16]([C:20](=[O:21])[NH:22][c:23]4[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]4)[c:17]3[cH:18][cH:19]2)[c:5]2[c:6]1[CH2:7][NH:8][CH2:9]2>>[n:1]1[cH:2][n:3][c:4]([O:10][c:11]2[cH:12][c:13]3[cH:14][cH:15][n:16]([C:20](=[O:21])[NH:22][c:23]4[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]4)[c:17]3[cH:18][cH:19]2)[c:5]2[c:6]1[CH2:7][N:8]([CH2:34][CH2:35][OH:36])[CH2:9]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d8e8c76882a9443aa782148d2e52d360
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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