反应详情

Compound 66 (3.7 mg, 0.0086 mmol) obtained in Example 68 was dissolved in ethyl acetate (2 mL), and 10% palladium-carbon (2.0 mg) was added thereto, followed by stirring at room temperature for 2 hours under a hydrgen atmosphere. The catalyst was sparated by filtration, followed by concentrating the filtrate to obtain the title compound (2.8 mg, 76%).

1. filtrationThe catalyst was sparated by filtration
2. concentrationby concentrating the filtrate