Dimethylformamide → N-(4-Chlorophenyl)-2-[(3,5-dichloropyridin-4-yl)amino]-7,7-dimethyl-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide

HRID 184715Notes

Reaction equation

HRID 184715 reaction equation
[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:26])[c:7]1[NH:8][c:9]1[nH:10][c:11]2[c:12]([n:13]1)[cH:14][c:15]([C:23](=[O:24])[OH:25])[c:16]1[c:17]2[CH2:18][C:19]([CH3:21])([CH3:22])[O:20]1.[Cl:54][c:55]1[cH:56][cH:57][c:58]([NH2:59])[cH:60][cH:61]1.[F:27][B-:28]([F:29])([F:30])[F:31].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[cH:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:26])[c:7]1[NH:8][c:9]1[nH:10][c:11]2[c:12]([n:13]1)[cH:14][c:15]([C:23](=[O:24])[NH:59][c:58]1[cH:57][cH:56][c:55]([Cl:54])[cH:61][cH:60]1)[c:16]1[c:17]2[CH2:18][C:19]([CH3:21])([CH3:22])[O:20]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 78124-ChloroanilineHCID 8028TetrahydrofuranHCID 26255TetrafluoroborateHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 178422814HCID 178422814, compound

Product 1

HCID 178422775N-(4-Chlorophenyl)-2-[(3,5-dichloropyridin-4-yl)amino]-7,7-dimethyl-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide

Sources & evidence

ORD record
ord-0fea0ef61dee4671961ce1b0f349d54f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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