N,N-Dimethylaniline → HCID 86630683, compound

HRID 1851206Notes

Reaction equation

HRID 1851206 reaction equation
[CH3:1][C:2]1[N:18]=[C:5]2[N:6]=[C:7](O)[C:8]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[C:9]([CH3:10])[N:4]2[N:3]=1.CN(C)C1C=CC=CC=1.O=P(Cl)(Cl)[Cl:30]>>[Cl:30][C:7]1[C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:9]([CH3:10])[N:4]2[N:3]=[C:2]([CH3:1])[N:18]=[C:5]2[N:6]=1

Participants

4

Reactant 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 178432406HCID 178432406, compound

Product 1

HCID 86630683HCID 86630683, compound

Conditions

Temperature
100 °C

Procedure

1.34 g of the product of step 1 were suspended in 20 mL POCl3. 1.06 mL N,N-dimethylaniline was added and the mixture was heated to 100° C. for 45 min. The excess of POCl3 was removed by distillation and the residue was treated with ice. The desired product precipitates and was collected by filtration.

Workup

  1. customThe excess of POCl3 was removed by distillation
  2. additionthe residue was treated with ice
  3. customThe desired product precipitates
  4. filtrationwas collected by filtration

Sources & evidence

ORD record
ord-d78e68c671a94f56b48a6248554837d6
Source dataset
uspto-grants-2015_02
Patent number
US08957064B2

Reaction notes

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