反应详情

A solution of 9.0 g 3,5-diamino-1,2,4-triazole and 22.4 mL diethyl phenylmalonate in N,N-dibutylbutan-1-amine was heated under microwave irradiation to 180° C. for 8 h. The reaction mixture formed two layers after cooling to room temperature. The top layer was removed and the solvent of the lower layer was evaporated. The residue was treated with water and acidified with 5N HCl. The precipitated product was collected by filtration and dried. The crude product was used without further purification.

1. customThe reaction mixture formed two layers
2. customThe top layer was removed
3. customthe solvent of the lower layer was evaporated
4. additionThe residue was treated with water
5. filtrationThe precipitated product was collected by filtration
6. customdried
7. customThe crude product was used without further purification