反应详情

A solution of pyridine-2-carbonitrile 20 g (192 mmol) and hydrazine hydrate (3 Eq.) in ethanol (50 mL) was stirred at room temperature for 18 hrs. The reaction mass was then diluted with water, extracted with ethyl acetate, and the organic portion dried (Na2SO4) and concentrated in vacuo to yield the desired compound.

1. extractionextracted with ethyl acetate
2. dry with materialthe organic portion dried (Na2SO4)
3. concentrationconcentrated in vacuo