反应详情

To a solution of 2.6 g 4-(4-Nitro-phenyl)-morpholin-3-one in 350 mL ethyl acetate and 17 mL ethanol, 13.2 g SnCl2 dihydrate were added and the reaction mixture was heated to reflux for 2 h. Then, after cooling to RT the mixture was stirred for 16 h. The precipitated product was collected by filtration and was pure enough for the next reaction step. Yield: 2.07 g.

1. temperaturethe reaction mixture was heated
2. temperatureto reflux for 2 h
3. filtrationThe precipitated product was collected by filtration
4. customwas pure enough for the next reaction step