HRID1853752

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31398

N-Chlorosuccinimide

C4H4ClNO2

结构：COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)N(C)C(=O)OC(C)(C)C)cc1

HCID86689443

未命名化合物

PRODUCTS

生成物

结构：COc1cc(Cl)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)N(C)C(=O)OC(C)(C)C)cc1

HCID68229126

未命名化合物

收率 20%

PROCEDURE

实验过程

Following General Procedure H, (R)-tert-butyl 1-(4-(8-methoxy-4-oxo-4,5-dihydrothieno[2,3-c]quinolin-9-yl)phenyl)ethyl(methyl)carbamate (200 mg, 0.43 mmol) was reacted with NCS (69 mg, 0.52 mmol) to afford the desired product (43 mg, 20%) as a yellowish solid. ESI MS m/z 499 [C26H27ClN2O4S+H]+.