Tetrahydrofuran → 2-Butyl-6-ethenyl-3-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4(3H)-quinazolinone

HRID 185592Notes

Reaction equation

HRID 185592 reaction equation
[Br:28][CH2:29][c:30]1[cH:31][cH:32][c:33](-[c:36]2[c:37](-[c:42]3[n:43][n:44][n:45][n:46]3[C:47]([c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)([c:54]3[cH:55][cH:56][cH:57][cH:58][cH:59]3)[c:60]3[cH:61][cH:62][cH:63][cH:64][cH:65]3)[cH:38][cH:39][cH:40][cH:41]2)[cH:34][cH:35]1.[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[nH:6][c:7]2[cH:8][cH:9][c:10]([CH:16]=[CH2:17])[cH:11][c:12]2[c:13](=[O:15])[n:14]1.[CH3:18][Si:19]([N-:20][Si:21]([CH3:22])([CH3:23])[CH3:24])([CH3:25])[CH3:26].[Li+:27].[O:66]1[CH2:67][CH2:68][CH2:69][CH2:70]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][c:10]([CH:16]=[CH2:17])[cH:11][c:12]2[c:13](=[O:15])[n:14]1[CH2:29][c:30]1[cH:31][cH:32][c:33](-[c:36]2[c:37](-[c:42]3[n:43][n:44][n:45][n:46]3[C:47]([c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)([c:54]3[cH:55][cH:56][cH:57][cH:58][cH:59]3)[c:60]3[cH:61][cH:62][cH:63][cH:64][cH:65]3)[cH:38][cH:39][cH:40][cH:41]2)[cH:34][cH:35]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 3280088Npc316347HCID 100534615-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazoleHCID 178435592HCID 178435592, compound

Product 1

HCID 152339312-Butyl-6-ethenyl-3-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4(3H)-quinazolinone

Sources & evidence

ORD record
ord-655652ba5b3a4dd9961c284b8560b85a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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