Hydrochloric Acid → (2-{4-[(1-Hydroxyethylidene)amino]benzene-1-sulfonyl}hydrazinylidene)acetic acid

HRID 1856217Notes

Reaction equation

HRID 1856217 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14](C(=O)C=O)[NH2:15])(=[O:13])=[O:12])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].O.[C:21]([OH:25])(=[O:24])[CH:22]=O.Cl>C(#N)C>[C:1]([NH:4][C:5]1[CH:6]=[CH:7][C:8]([S:11]([NH:14][N:15]=[CH:22][C:21]([OH:25])=[O:24])(=[O:12])=[O:13])=[CH:9][CH:10]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 15620607Glyoxylic acid, monohydrateHCID 86737152HCID 86737152, compound

Product 1

HCID 321926(2-{4-[(1-Hydroxyethylidene)amino]benzene-1-sulfonyl}hydrazinylidene)acetic acid

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The subject compound is prepared using the general method of Example 1 except that 4.58 g (20 mmol) of glyoxylic acid p-acetamidobenzenesulfonylhydrazide was reacted with 2.4 g (26 mmol) of glyoxylic acid monohydrate in the presence of 1/2 cc conc. HCl and 200 cc acetonitrile. The desired product was obtained in a yield of 5.4 g, m.p. 136° (dec.).

Workup

  1. customThe subject compound is prepared

Sources & evidence

ORD record
ord-cbcbf5377c674adf8ad789d2649b79d3
Source dataset
uspto-grants-1980_08
Patent number
US04218465

Reaction notes

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