Diboron → HCID 23346423, compound

HRID 1856224Notes

Reaction equation

HRID 1856224 reaction equation
[F:1][C:2]([F:20])([F:19])[C:3]1[C:11]([C:12]([F:15])([F:14])[F:13])=[CH:10][CH:9]=[C:5]([C:6](O)=[O:7])[C:4]=1[C:16](O)=[O:17].B#B>O1CCCC1>[F:1][C:2]([F:19])([F:20])[C:3]1[C:11]([C:12]([F:14])([F:15])[F:13])=[CH:10][CH:9]=[C:5]([CH2:6][OH:7])[C:4]=1[CH2:16][OH:17]

Participants

4

Reactant 2

HCID 6328200DiboronHCID 18787738HCID 18787738, compound

Product 1

HCID 23346423HCID 23346423, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

3,4-Bis(trifluoromethyl)phtalic acid (33 g., 0.11 mol.) in 70 ml. of tetrahydrofuran is refluxed with 450 ml. of 1.0 M diborane in tetrahydrofuran for four hours. Excess diborane is destroyed with water to yield 3,4-bis(trifluoro- methyl)-1,2-benzenedimethanol.

Workup

  1. customExcess diborane is destroyed with water

Sources & evidence

ORD record
ord-9c417a032c974407846dcfb69957086f
Source dataset
uspto-grants-1980_08
Patent number
US04218464

Reaction notes

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