反应详情

温度

150 °C

Then, sodium bromide (43.01 g, 0.42 mol) and sodium benzoate (60.24 g, 0.42 mol) were added to a mixture of the above 4-chloromethyl-2,2-dimethyl-1,3-dioxolane (60.02 g, 0.39 mol) and N,N-dimethylformamide (600 ml) and the resulting mixture was stirred for 15 hours at 150° C. After cooling the salt was filtered off and N,N-dimethylformamide was removed in vacuo and water was added to the residue and extracted with toluene. The extract was washed with saturated brine, dried over anhydrous sodium sulfate and condensed in vacuo to give crude 4-benzoyloxymethyl-2,2-dimethyl-1,3-dioxolane (yield 90%).

1. temperatureAfter cooling the salt
2. filtrationwas filtered off
3. customN,N-dimethylformamide was removed in vacuo and water
4. additionwas added to the residue
5. extractionextracted with toluene
6. washThe extract was washed with saturated brine
7. dry with materialdried over anhydrous sodium sulfate and condensed in vacuo