3-Methoxybenzenethiol → HCID 22132683, compound

HRID 1857113Notes

Reaction equation

HRID 1857113 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([SH:24])[CH:21]=[CH:22][CH:23]=1>>[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][C:8]=1[O:14][CH3:15])[N:5]=[CH:4][CH:3]=[C:2]2[S:24][C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([O:17][CH3:16])[CH:19]=1

Participants

3

Reactant 2

HCID 849893-MethoxybenzenethiolHCID 4596104-Chloro-6,7-dimethoxyquinoline

Product 1

HCID 22132683HCID 22132683, compoundYield 100%

Conditions

Temperature
180 °C

Procedure

4-Chloro-6,7-dimethoxyquinoline (50 mg) and commercially available 3-methoxybenzenethiol (77 mg) were mixed and stirred at 180° C. for 30 seconds. Purification was carried out in the same manner as described in Example 18 to obtain 72 mg of the title compound (yield: 100%).

Workup

  1. customPurification

Sources & evidence

ORD record
ord-a80957b74fba4db7af0ea9dacbaa494f
Source dataset
uspto-grants-2000_11
Patent number
US06143764

Reaction notes

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