Oxalic Acid → 1,4-Dihydrobenzo[g]quinoxaline-2,3-dione

HRID 1857414노트

반응식

HRID 1857414 반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([NH2:11])[C:2]=1[NH2:12].[C:13](O)(=[O:17])[C:14](O)=[O:15]>Cl>[NH:12]1[C:2]2[CH:1]=[C:10]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]3=[CH:4][C:3]=2[NH:11][C:14](=[O:15])[C:13]1=[O:17]

참가 물질

4

반응물 2

HCID 971Oxalic AcidHCID 698722,3-Diaminonaphthalene

생성물 1

HCID 108224091,4-Dihydrobenzo[g]quinoxaline-2,3-dione수율 99.3%

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

A mixture of 603 mg (3.81 mmol) of 2,3-naphthalenediamine and 382 mg (4.24 mmol) of oxalic acid in 5 mL of 2N HCl was refluxed for 3 h and cooled to room temperature. The mixture was filtered, washed with water, and dried to leave a brown solid 803 mg (99%); mp>250° C.; 1H NMR (DMSO-d6), 7.382 (dd, 2, J=3.16, 6.17), 7.525 (s, 2), 7.815 (dd, 2, J=3.22, 6.18), 12.088 (s, 2).

후처리

  1. temperaturewas refluxed for 3 h
  2. filtrationThe mixture was filtered
  3. washwashed with water
  4. customdried

출처 및 근거

ORD 기록
ord-04096a12898c48c485ae8d4764847c6a
출처 데이터셋
uspto-grants-2000_11
특허 번호
US06147075

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