Hydrochloric Acid → HCID 15484978, compound

HRID 1857584Notes

Reaction equation

HRID 1857584 reaction equation
[CH:1]1([S:6]([NH2:9])(=[O:8])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].[Cl:12][C:13]1[CH:14]=[C:15]([N:20]=[C:21]=[O:22])[CH:16]=[CH:17][C:18]=1[Cl:19].Cl>CC(C)=O.O>[Cl:12][C:13]1[CH:14]=[C:15]([NH:20][C:21]([NH:9][S:6]([CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)(=[O:8])=[O:7])=[O:22])[CH:16]=[CH:17][C:18]=1[Cl:19]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 76073,4-Dichlorophenyl isocyanateHCID 14798Sodium HydroxideHCID 4645983Cyclopentanesulfonamide

Product 1

HCID 15484978HCID 15484978, compoundYield 85.2%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolvent2×HCID 962WaterSolvent

Procedure

The general method of procedure A was followed with cyclopentanesulfonamide (3 g), acetone (200 ml), 1N sodium hydroxide (20 ml), and 3,4-dichlorophenyl isocyanate (3.6 g) dissolved in acetone (50 ml). After two hours, 1N HCl (20 ml) was added and the resulting solid diluted with water and collected. After drying at 65° C., 5.5 g of solid product were obtained.

Workup

  1. customcollected
  2. customAfter drying at 65° C.

Sources & evidence

ORD record
ord-83b3f892b59f493092b1d9beb4ac4ce3
Source dataset
uspto-grants-2000_11
Patent number
US06147115

Reaction notes

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