反应详情

A solution of 97.5 g of 2-bromo-α-bromoacetophenone in 200 ml of acetone is poured dropwise, at ambient temperature, into a solution of 61.7 g de N-benzyl-2-cyanoethylamine and 67 ml of diisopropylethylamine in 200 ml of acetone. After stirring for 12 hours, the reaction mixture is evaporated, taken up in ether, washed twice with 500 ml of water each time and dried. After evaporating under reduced pressure, 131.9 g of expected product are obtained.

1. customthe reaction mixture is evaporated
2. washwashed twice with 500 ml of water each time
3. customdried
4. customAfter evaporating under reduced pressure, 131.9 g of expected product
5. customare obtained