Aluminium lithium hydride → HCID 86756069, compound

HRID 1859055Notes

Reaction equation

HRID 1859055 reaction equation
[CH2:1]([N:8]1[CH2:12][C@:11]2([CH2:19][C:20](O)=[O:21])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C@@H:10]2[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH2:1]([N:8]1[CH2:12][C@:11]2([CH2:19][CH2:20][OH:21])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C@@H:10]2[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 86756070HCID 86756070, compound

Product 1

HCID 86756069HCID 86756069, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3.32 g of the product obtained in Step C are introduced, in portions, into a suspension composed of 0.73 g of lithium aluminium hydride and 53 ml of tetrahydrofuran. After 2 hours at ambient temperature, the medium is hydrolysed in the cold state and the precipitate formed is filtered off. After evaporating off the solvent, the expected product is isolated.

Workup

  1. customthe precipitate formed
  2. filtrationis filtered off
  3. customAfter evaporating off the solvent

Sources & evidence

ORD record
ord-815f1672dee14c5dad411a051ac53e2c
Source dataset
uspto-grants-2000_11
Patent number
US06153640

Reaction notes

Loading…