3-Amino-4-methoxybenzanilide → HCID 18626247, compound

HRID 1859745Notes

Reaction equation

HRID 1859745 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6](Cl)(=[O:8])=[O:7].[NH2:10][C:11]1[CH:12]=[C:13]([CH:23]=[CH:24][C:25]=1[O:26][CH3:27])[C:14]([NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:15]>N1C=CC=CC=1>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([NH:10][C:11]1[CH:12]=[C:13]([CH:23]=[CH:24][C:25]=1[O:26][CH3:27])[C:14]([NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:15])(=[O:8])=[O:7]

Participants

4

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 855182-Thiophenesulfonyl chloride

Product 1

HCID 18626247HCID 18626247, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared according to the procedure described for Example 121 using 2-thiophenesulfonyl chloride (1.82 g, 10 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10 mmol), and pyridine (25 mL) to afford the product (3.457 g); m.p. 180-183° C. after trituration in hexanes/ethyl acetate (1:1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-99e5a32a609245558ef4b04de6261ff1
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

Loading…