p-Toluenesulfonic acid → HCID 18626564, compound

HRID 1859765Notes

Reaction equation

HRID 1859765 reaction equation
[NH2:1][CH2:2][C:3]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:4][OH:5].[Cl:18][C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][CH:20]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[Cl:18][C:19]1[CH:26]=[CH:25][C:22]([CH:23]2[NH:1][CH2:2][C:3]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)([C:6]3[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=3)[CH2:4][O:5]2)=[CH:21][CH:20]=1

Participants

5

Reactant 3

HCID 6101p-Toluenesulfonic acidHCID 77264-ChlorobenzaldehydeHCID 18626554HCID 18626554, compound

Product 1

HCID 18626564HCID 18626564, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This product is obtained by reacting 3-amino-2,2-diphenyl-1-propanol with 4-chlorobenzaldehyde in refluxing toluene in the presence of p-toluenesulphonic acid for 5 hours.

Workup

  1. customThis product is obtained

Sources & evidence

ORD record
ord-4dd1cf7d417441488ac7c37ac5df56d1
Source dataset
uspto-grants-2003_03
Patent number
US06528538B1

Reaction notes

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