Dichloromethane → 1-benzo[1,3]dioxol-5-yl-N-[3-[4-(methylsulfamoyl)phenyl]phenyl]-cyclopropane-1-carboxamide

HRID 186060Notes

Reaction equation

HRID 186060 reaction equation
[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:44][N:45]([c:46]1[cH:47][cH:48][n:49][cH:50][cH:51]1)[CH3:52].[Cl:41][CH2:42][Cl:43].[NH2:16][c:17]1[cH:18][c:19](-[c:23]2[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[NH:32][CH3:33])[cH:27][cH:28]2)[cH:20][cH:21][cH:22]1.[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[Cl:15])[CH2:11][CH2:12]1)[cH:9]2>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[NH:16][c:17]3[cH:18][c:19](-[c:23]4[cH:24][cH:25][c:26]([S:29](=[O:30])(=[O:31])[NH:32][CH3:33])[cH:27][cH:28]4)[cH:20][cH:21][cH:22]3)[CH2:11][CH2:12]1)[cH:9]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 591291541-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarbonyl chlorideHCID 592061913'-amino-N-methylbiphenyl-4-sulfonamide

Product 1

HCID 592059751-benzo[1,3]dioxol-5-yl-N-[3-[4-(methylsulfamoyl)phenyl]phenyl]-cyclopropane-1-carboxamide

Sources & evidence

ORD record
ord-0304e942f0d344828f45fd87c7dd6122
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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