Acetonitrile → 4-(4-Hydroxy-but-1-ynyl)-thiophene-2-carboxylic acid methyl ester
Reaction equation
[Br:20][c:21]1[cH:22][c:23]([C:26](=[O:27])[O:28][CH3:29])[s:24][cH:25]1.[CH2:37]([CH2:38][C:39]#[CH:40])[OH:41].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:42][C:43]#[N:44].[Cu:48].[Pd:45]([Cl:46])[Cl:47].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[c:21]1([C:40]#[C:39][CH2:38][CH2:37][OH:41])[cH:22][c:23]([C:26](=[O:27])[O:28][CH3:29])[s:24][cH:25]1Participants
8
Sources & evidence
- ORD record
- ord-8f9896f69ebe45df8eef46c2e06dcb88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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