3-Nitrobenzaldehyde → Benzenemethanamine, N-ethyl-3-nitro-

HRID 1861954Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)([O-:3])=[O:2].Cl.[CH2:13]([NH2:15])[CH3:14]>>[N+:1]([C:4]1[CH:5]=[C:6]([CH2:7][NH:15][CH2:13][CH3:14])[CH:9]=[CH:10][CH:11]=1)([O-:3])=[O:2]

Participants

Reactant 2

HCID 74493-Nitrobenzaldehyde

HCID 11198Ethylamine hydrochloride

Product 1

HCID 485409Benzenemethanamine, N-ethyl-3-nitro-Yield 47%

Procedure

Using m-nitrobenzaldehyde as a starting material and also using ethylamine hydrochloride as a reagent, the same procedure of Example 42 gave 2.8 g of the titled compound (yield, 47%).

Sources & evidence

ORD record: ord-a61db990d19346e4b2c50147f6eb3a01
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06534546B1

Reaction notes

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