Chloride → HCID 20393730, compound

HRID 1862826Notes

Reaction equation

HRID 1862826 reaction equation
[CH:1]([NH:4][C:5]1[C:18]2[C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][C:15]=3[OH:20])[C:10](=[O:21])[C:9]=2[C:8](Br)=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[CH:23]1([NH2:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1.C([O-])(=O)C.[K+].[Cl-]>CO>[CH:1]([NH:4][C:5]1[C:18]2[C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][C:15]=3[OH:20])[C:10](=[O:21])[C:9]=2[C:8]([NH:29][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[CH:7][CH:6]=1)([CH3:3])[CH3:2]

Participants

6

Reactant 4

HCID 312ChlorideHCID 7965CyclohexylamineHCID 517044Potassium AcetateHCID 20393733HCID 20393733, compound

Product 1

HCID 20393730HCID 20393730, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

18 g of 1-isopropylamino-4-bromo-8-hydroxy-anthraquinone, 36 ml of cyclohexylamine, 6.5 of potassium acetate and catalytic amounts of copperI chloride are stirred at 80°-90° until only a little starting material is still detectable. The mixture is now diluted with 36 ml of methanol and the reaction product which has separated out is filtered off at 60°, washed with boiling hot methanol, finally stirring with dilute hydrochloric acid, filtered off, washed until neutral and dried.

Workup

  1. customthe reaction product which has separated out
  2. filtrationis filtered off at 60°
  3. washwashed
  4. filtrationfiltered off
  5. washwashed until neutral and
  6. customdried

Sources & evidence

ORD record
ord-534cd7aade6f46d5bf3e65d37988f0c0
Source dataset
uspto-grants-1979_09
Patent number
US04166822

Reaction notes

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