3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine
Reaction equation
Brc1cccnc1.c1ccc(C2CCNCC2)cc1>CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[Fe].[Pd]>c1ccc(C2CCN(c3cccnc3)CC2)cc1Participants
6
Workup
- additionsolution of bipheny (3%) and acetic acid to quench reaction. Acetic acid amount not specified.
- aliquotNo procedure recorded
- additionNo procedure recorded
Sources & evidence
- ORD record
- ord-514a6b6c588848bf82246144031bcf6d
- Source dataset
- Pd-catalyzed Buchwald-Hartwig C-N cross-coupling
- Original link
- View source
Reaction notes
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