反应详情

Add potassium carbonate (2.20 g, 15.92 mmol) to 2-bromobenzenethiol (2.00 g, 10.58 mmol) in acetone and stir at room temperature. After 10 minutes, add iodoethane (1.82 g, 11.67 mmol) with stirring. After 18 hours, add water and extract with ethyl acetate. Combine the organic extracts, wash with water and brine, dry over anhydrous magnesium sulfate, filter, and concentrate under reduced pressure. Purify the residue by flash chromatography eluting with ethyl acetate:hexanes to provide the title compound.

1. stirringwith stirring
2. waitAfter 18 hours
3. extractionextract with ethyl acetate
4. washwash with water and brine
5. dry with materialdry over anhydrous magnesium sulfate
6. filtrationfilter
7. concentrationconcentrate under reduced pressure
8. customPurify the residue by flash chromatography
9. washeluting with ethyl acetate