Chloromethyl chloroformate → HCID 68667057, compound

HRID 1865390Notes

Reaction equation

[Cl:1][CH2:2][O:3][C:4](Cl)=[O:5].[NH:7]1[CH2:17][CH2:16][CH:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:9][CH2:8]1>>[Cl:1][CH2:2][O:3][C:4]([N:7]1[CH2:8][CH2:9][CH:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:16][CH2:17]1)=[O:5]

Participants

Reactant 2

HCID 62754Chloromethyl chloroformate

HCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 68667057HCID 68667057, compound

Procedure

Using chloroformic acid chloromethyl ester and ethyl isonipecotate as the raw materials, the same operation as the Example 101(1) gave the title compound as a crude product, and the crude product was used for the next reaction without further purification.

Sources & evidence

ORD record: ord-3331d702c8ba4643afd619fbbb3a6858
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07626042B2

Reaction notes

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