Dichloromethane → N-{3-[5-(3-methyl-5-{[4-(trifluoromethyl)-pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]oxetan-3-yl}methanesulfonamide
Reaction equation
[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:36][S:37]([Cl:38])(=[O:39])=[O:40].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[Cl:41][CH2:42][Cl:43].[NH2:1][C:2]1([c:6]2[s:7][c:8](-[c:11]3[cH:12][c:13]([NH:18][c:19]4[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]4)[cH:14][c:15]([CH3:17])[cH:16]3)[cH:9][n:10]2)[CH2:3][O:4][CH2:5]1>>[NH:1]([C:2]1([c:6]2[s:7][c:8](-[c:11]3[cH:12][c:13]([NH:18][c:19]4[n:20][cH:21][cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]4)[cH:14][c:15]([CH3:17])[cH:16]3)[cH:9][n:10]2)[CH2:3][O:4][CH2:5]1)[S:37]([CH3:36])(=[O:39])=[O:40]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-67546ea0027549ac88c4e3244178941d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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