O-Cresol → 1-(tert-Butoxycarbonyl)-4-cyano-4-(2-methylphenoxymethyl)piperidine
Reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][C:21]([CH2:24][O:25][S:26]([CH3:27])(=[O:28])=[O:29])([C:30]#[N:31])[CH2:22][CH2:23]1.[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[OH:8].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[H-:9].[Na+:10].[OH2:32]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[O:8][CH2:24][C:21]1([C:30]#[N:31])[CH2:20][CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:23][CH2:22]1Participants
7
Sources & evidence
- ORD record
- ord-7e0233e99bbc49bb9d5520631698430e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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