反应详情

温度

170 °C

N′-Phenyl-2-pyridin-4-ylacetohydrazide (460 mg, 2.02 mmol) and calcium hydride (141 mg, 3.34 mmol) were dissolved in dimethylformamide (8 mL) and heated at 170° C. After 8 h, the reaction cooled to ambient temperature and was filtered. The mixture was concentrated and redissolved in dichloromethane (50 mL). The precipitate was filtered and dried under high vacuum overnight to give the desired product. MS 238.04 (M+1)

1. temperaturethe reaction cooled to ambient temperature
2. filtrationwas filtered
3. concentrationThe mixture was concentrated
4. dissolutionredissolved in dichloromethane (50 mL)
5. filtrationThe precipitate was filtered
6. customdried under high vacuum overnight