反应详情

A mixture of EXAMPLE 1B (2.96 g), (S)-prolinol (850 μL), and diisopropylethylamine (4 mL) in acetonitrile (70 mL) at 25° C. was stirred for 3 days, treated with water, and extracted with dichloromethane. The extract was washed with 1M hydrochloric acid, water, saturated NaHCO3, and water, and concentrated.

1. extractionextracted with dichloromethane
2. washThe extract was washed with 1M hydrochloric acid, water, saturated NaHCO3, and water
3. concentrationconcentrated