Hydrochloric Acid → HCID 69084767, compound

HRID 1867940Notes

Reaction equation

HRID 1867940 reaction equation
[CH3:1][O:2][C:3]1[CH:52]=[C:51]([O:53][CH3:54])[CH:50]=[CH:49][C:4]=1[CH2:5][N:6]1[C:15]2[C:10](=[CH:11][C:12]([F:42])=[C:13]([N:16]3[CH2:20][CH2:19][CH2:18][CH:17]3[CH2:21][NH:22][C:23]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[N:14]=2)[C:9](=[O:43])[C:8]([C:44]([O:46]CC)=[O:45])=[CH:7]1.[OH-].[Li+].Cl>C(O)C>[CH3:1][O:2][C:3]1[CH:52]=[C:51]([O:53][CH3:54])[CH:50]=[CH:49][C:4]=1[CH2:5][N:6]1[C:15]2[C:10](=[CH:11][C:12]([F:42])=[C:13]([N:16]3[CH2:20][CH2:19][CH2:18][CH:17]3[CH2:21][NH:22][C:23]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)[C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=3)[N:14]=2)[C:9](=[O:43])[C:8]([C:44]([OH:46])=[O:45])=[CH:7]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 69027586HCID 69027586, compound

Product 1

HCID 69084767HCID 69084767, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of EXAMPLE 7B (1.7 g) and 0.1M lithium hydroxide (40 mL) in ethanol (80 mL) was stirred for 18 hours, adjusted to pH 5 with 1M hydrochloric acid, and filtered.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-67e96fe620f644ea901ec3f744030d62
Source dataset
uspto-grants-2009_12
Patent number
US07632946B2

Reaction notes

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