Acetic Acid → 2'-({[Tert-butyl(dimethyl)silyl]oxy}methyl)-4-fluoro-5-isopropyl-2-methoxy-4'-(trifluoromethyl)biphenyl-3-ol
Reaction equation
[C:6]([CH3:7])([CH3:8])([CH3:9])[Si:10]([CH3:11])([CH3:12])[O:13][CH2:14][c:15]1[c:16](-[c:25]2[c:26]([O:35][CH3:36])[cH:27][c:28]([F:34])[c:29]([CH:31]([CH3:32])[CH3:33])[cH:30]2)[cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[cH:20]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:37][O:38][B:39]([O:40][CH3:41])[O:42][CH3:43].[CH3:44][C:45](=[O:46])[OH:47].[OH2:55].[OH:48][OH:49]>>[C:6]([CH3:7])([CH3:8])([CH3:9])[Si:10]([CH3:11])([CH3:12])[O:13][CH2:14][c:15]1[c:16](-[c:25]2[c:26]([O:35][CH3:36])[c:27]([OH:38])[c:28]([F:34])[c:29]([CH:31]([CH3:32])[CH3:33])[cH:30]2)[cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[cH:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4eb1dac87393428fa34d657807f85c5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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