Cyclobutanecarboxylic acid → 1-(Cyclopropylmethyl)cyclobutane-1-carboxylic acid

HRID 1868438Notes

Reaction equation

[CH:1]1([C:5]([OH:7])=[O:6])[CH2:4][CH2:3][CH2:2]1.Br[CH2:9][CH:10]1[CH2:12][CH2:11]1>>[CH:10]1([CH2:9][C:1]2([C:5]([OH:7])=[O:6])[CH2:4][CH2:3][CH2:2]2)[CH2:12][CH2:11]1

Participants

Reactant 2

HCID 19494Cyclobutanecarboxylic acid

HCID 81503Bromomethylcyclopropane

Product 1

HCID 450847861-(Cyclopropylmethyl)cyclobutane-1-carboxylic acid

Procedure

The title compound was prepared according to the procedure described for Intermediate 15.1 from cyclobutanecarboxylic acid and (bromomethyl)cyclopropane.

Sources & evidence

ORD record: ord-771c909f7a164914b42adf84818579ee
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07635713B2

Reaction notes

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