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HRID1869773

反应详情

EQUATION

反应方程式

HRID 1869773 的结构方程式

REACTANTS

反应物

3
反应SMILES：O=Cc1ccc(Cl)cc1
HCID7726

4-Chlorobenzaldehyde

C7H5ClO

反应SMILES：CC(C)CCBr
HCID7891

1-Bromo-3-methylbutane

C5H11Br

反应SMILES：CC(C(=O)[O-])[C@@H]1CCN[C@H](c2ccc(C(F)(F)F)cc2)C1
HCID86617999

未命名化合物

PRODUCTS

产物

1
反应SMILES：CC(C)CC[C@H](c1ccc(Cl)cc1)N1CC[C@@H](CC(=O)O)C[C@H]1c1ccc(C(F)(F)F)cc1
HCID57987388

未命名化合物

PROCEDURE

实验过程

The compound was prepared analogously to Example 160 using the Grignard reagent derived from 1-bromo-3-methylbutane, starting with the chiral piperidine of Example 114 Step 1 and replacing 4-(trifluoromethyl)benzaldehyde with 4-chlorobenzaldehyde. M/Z (ES+) 482 (M+H).